Advocate Flea Control for Dogs – How to use the spot on treatment and FAQ's


How to use advocate for dogs

What is Advocate?

Advocate is a spot-on insecticide treatment which comes in a liquid form and is applied to the skin on the back of the animal’s neck. It is a yellow-brown solution which contains the active ingredients imidacloprid and moxidectin and it is used to treat a range of parasites in dogs, cats and ferrets. Advocate comes in several concentrations so that different sizes of pets can be given accurate doses. Bayer manufactures the treatment which comes in small white pipettes, either in packets of 3 or 6.

Are you shopping for Advocate for Dogs? Click here to view the range

Advocate is a prescription only medication (POM-V drug) which means it can only be obtained from your vet or via a prescription from them. If your vet prescribes the medication for you, you can then take that prescription to purchase the spot-on treatment elsewhere at a reduced cost – such as an online dispensary or pharmacy.

What is Advocate used for?

Advocate is used to treat and prevent fleas (Ctenocephalides felis) in both dogs and cats and can be used as part of a routine treatment regime for flea allergic dermatitis (FAD). Advocate is also used to treat against ear mites (Otodectes cyanotis) and can be used in the prevention of heartworm (Dirofilaria immitis) and several intestinal worms in dogs and cats including roundworm, heartworm, lungworm and whipworm. These worms are also known by their scientific Latin names: Ancylostoma spp, Toxocara spp, Uncinaria stenocephala and Trichuris vulpis.

In dogs specifically, Advocate can be used to treat biting lice (Trichodectes canis), sarcoptic mange caused by the mite Sarcoptes scabeii and demodecosis, a skin disease caused by another mite Demodex canis.

In ferrets, Advocate is used to treat and prevent fleas and also to prevent heartworm.

Advocate Dosage and Administration

Advocate is applied topically to the skin on the back of the neck – usually once a month or every four weeks. It should be applied to an area where your pet cannot reach to lick it off, usually between the shoulder blades.

Advocate Spot On TreatmentHow to use advocate for dogs

The dose of Advocate required will depend on your pet’s weight and comes in several strengths so that any sized animal can be given an accurate dose. Advocate can be given safely alongside most veterinary medicines.

Dogs – 10mg/kg bodyweight imidacloprid and 2.5mg/kg bodyweight moxidectin. This equates to 0.1ml/kg bodyweight Advocate dog solution.

Cats – 10mg/kg imidacloprid and 1mg/kg moxidectin. This equates to 0.1ml/kg Advocate cat solution.

Ferrets – These should be given one pipette of small cat/ferret Advocate.

A table showing which size of Advocate is needed for animals of differing weights is shown below


Weight of Cat (kg)

Size of Advocate

Volume of Advocate (ml)


Small cat/ferret



Large cat



Appropriate combination of pipettes


 Advocate Range


Weight of Dog (kg)

Size of Advocate

Volume of Advocate (ml)


Small dog & puppy



Medium dog



Large dog



Extra Large



Appropriate combination of pipettes


The dosing regimen for each specific parasite is as follows:

Fleas: One pipette every 4 weeks in dogs and cats to treat and then prevent recurrence. In ferrets one pipette is needed every 3 weeks and can be given every 2 weeks if there is a large burden of fleas

Ear mites: A single dose is usually enough to treat ear mites but a recheck with your vet is advised after a month as a further dose may be needed.

Lice: A single dose will kill most biting lice but a second dose may be required a month later so a recheck with your vet is advised.

Sarcoptes: 2 doses, 4 weeks apart are needed to treat sarcoptic mange

Demodex: A dose of Advocate monthly for 2-4 months is usually needed to treat demodecosis but treatment should be continued until 2 consecutive skin scrapes have tested negative for the demodex mite.

Heartworm: Advocate should be given monthly throughout the mosquito season as heartworm is transmitted by mosquitoes. Advocate should be started at least a month before the season starts.

Roundworms: In both cats and dogs, Advocate should be applied monthly to treat and prevent intestinal roundworms.

How to manage a flea infestation

Frequently asked Questions

Q. What is Advocate?                                                                                                                                 

A. Advocate is a liquid containing insecticide to prevent parasite infestations.

Q. What does Advocate treat?                                                                                                                          

A. Flea, mites, lice, intestinal worms and heartworm.

Q. How is Advocate given?                                                                                                                    

A. Using a pipette liquid that is applied topically to the skin on the back of the neck

Q. How often is Advocate given?                                                                                                                          

A. Best given monthly (or every four weeks) to both treat and prevent further infestations of parasites.

Q. Does Advocate have any side effects?                                                                                                           

A. Advocate may cause a local skin irritation and can cause salivation and vomiting if it is ingested.

Q. How much Advocate does my pet need?                                                                                             

A. The dose will depend on your pet’s weight and your vet will advise which size of Advocate is needed.

Q. I have run out of cat Advocate, can I give my cat the small dog dose?                                                    

A. No, the concentration of active ingredients is different in dog and cat advocate so you must use the correct product.

Q. I applied Advocate to my dog a few days ago but have seen a flea on the sofa, should I apply more?                 

A. No, it would be best to use an environmental insecticide spray in your home. If your dog is still itchy then contact your vet for advice.

Q. I have a 6-week-old kitten and I can see fleas on her, can I give Advocate?                                                       

A. No, Advocate cannot be used on kittens under 9 weeks. You should ask your vet for advice.

Q. Members of my family have accidentally applied Advocate twice this week, should I worry?                                                                                                                                                                   

A. Advocate has been tested at several times the recommended dose and has been found to be safe but keep an eye on the area of application and if you see any adverse effects then call your vet for advice.

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