Disease and Illnesses of dogs – Heart Failure- Vasotop

What is Vasotop?

Vasotop is a drug that is used in the management of congestive heart failure in dogs. Vasotop is manufactured by Intervet Schering-Plough and is available in three sizes of tablets, 1.25mg, 2.5mg and 5mg. Ramipril is the active ingredient in Vasotop which belongs to a class of drugs called Angiotensin Converting Enzyme Inhibitors. Vasotop tablets are given once daily with food.

 What is Vasotop used for?

Vasotop is used to treat cases of decompensated congestive heart failure in dogs. The clinical signs associated with heart failure as well as the prognosis improve when giving Vasotop as it helps to support the cardiovascular system. Vasotop is often used with other drugs also designed to support heart function, specifically diuretics such as frusemide, used to stop the lungs filling with fluid and a drug called digoxin which is used to treat abnormal heart rhythms.

 Vasotop Tips

  • The dose of Vasotop is based on weight so weigh your pet regularly
  • You should only give Vasotop to your pet if directed by a vet to do so
  • Vasotop is usually given once a day
  • If you see any side effects after giving Vasotop then call your vet
  • Vasotop is available in three sizes to improve accuracy of dosing
  • Contact your vet immediately if you suspect an overdose of Vasotop
  • Vasotop will often be given along with other drugs
  • Store Vasotop in a  dry place, under 30oC
  • Keep Vasotop out of reach of children

 Side Effects

  • Vomiting, diarrhoea and anorexia are the main side effects that are seen
  • Call your vet if you suspect any adverse reactions to Vasotop
  • Low blood pressure may occur at higher doses of Vasotop
  • Higher doses of Vasotop may cause lethargy
  • You must be careful giving Vasotop with other drugs that can lower blood pressure
  • Vasotop should be used cautiously in animals with existing kidney disease
  • Kidney parameters should be monitored while on treatment with Vasotop
  • No information is available about the use of Vasotop in pregnant bitches

Dosage and Administration

  • Vasotop comes in 1.25mg, 2.5mg and 5mg tablets
  • Vasotop tablets are scored to make dividing them easier
  • The dose of Vasotop will be calculated according to the weight of your pet
  • Your vet will advise you on the correct dose of Vasotop
  • Vasotop is given once daily
  • Vasotop can be given with food
  • The dose can be increased with severe disease but this will be decided by your vet
  • Do not change the dose of Vasotop without consulting your vet.
  • Vasotop can be given with other medications

Further Information about Vasotop

Vasotop is a drug used in the management of congestive heart failure in dogs and contains the active ingredient Ramipril. Vasotop is available in 1.25mg, 2.5mg and 5mg tablets and the exact dose will depend on the weight of your pet. Vasotop is a POM-V class drug which means it needs to be prescribed by the vet who is looking after your pet.

Ramipril is part of a class of drugs called Angiotensin Converting Enzyme Inhibitors. Vasotop will reduce the conversion of Angiotensin I to Angiotensin II. Angiotensin II causes constriction of blood vessels which increases the resistance that the heart has to pump against. Vasotop will therefore reduce this resistance, helping the heart to pump blood more effectively. The ramipril in Vasotop is converted to ramiprilat, the active form, in the liver.

Vasotop can be given once daily with food. Occasionally side effects such as vomiting, diarrhoea and anorexia can be seen. At higher doses of Vasotop and sometimes after a dose change animals can seem lethargic and have an unsteady gait. Call your vet if you see any potential side effects from Vasotop.

Further information about dosing and administration of Vasotop

The dose of Vasotop in dogs is 1.25mg ramipril per kilogram of your pet’s bodyweight. It is therefore important that you weigh your pet regularly so that the dose is always accurate. The dose is given once daily with, 1.25mg, 2.5mg or 5mg tablets or a combination. Vasotop 1.25mg tablets are beige and scored for easy dividing. Vasotop 2.5mg tablet are yellow in colour and scored and Vasotop 5mg are pink in colour and again, scored so they can be divided.

This dose of Vasotop can be increased after two weeks in cases of severe disease but this should only be done under the supervision and guidance of your vet. Vasotop tablets can be given with food or directly into the mouth. Vasotop is often given in conjunction with other drugs to better control the heart failure.

The dosage chart below shows a suggested dosing schedule for Vasotop.

Bodyweight (kg)

1.25mg Vasotop

2.5mg Vasotop

5mg Vasotop

2.6-5

½

 

 

6-10

1

 

 

11-20

 

1

 

21-40

 

 

1

41-50

1

 

1

51-60

 

1

1

  

Frequently asked questions

Q. What does Vasotop do?                                                                                                                              

A. Vasotop helps improve the quality of life of dogs with heart failure but helping the heart to pump more effectively

 

Q. How much Vasotop should I give my dog?                                                                                                                

A. The exact dose is based on your pet’s weight and will be decided by your vet but the above table gives a suggested dose rate.

 

Q. Can I split the Vasotop tablet?                                                                                                                            

A. Yes, Vasotop tablets are designed to be split in half for more accurate dosing.

 

Q. How long will my dog need to be taking Vasotop?                                                                                              

A. Once treatment is started it is usually required for the rest of the dog’s life as heart failure is managed rather than cured.

 

Q. How is Vasotop administered?                                                                                                                           

A. Vasotop must be given by mouth but can be given once daily in food.

 

Q. Does Vasotop have any side effects?                                                                                                                             

 A. Vasotop can occasionally have side effects such as vomiting, diarrhoea, anorexia and lethargy. If you see any of these problems then call your vet for advice.

 

Q. What should I do if I give my pet an extra dose of Vasotop by mistake?                                                               

A. Call your vet immediately for advice and monitor your pet for any problems.

 

Q. Does it matter if I miss a dose of Vasotop by mistake?                                                                                            

A. It is always best to adhere closely to the dose regime advised by your vet but if you miss a dose then just give the next dose as normal, don’t give double the dose next time.

 

Q. Is it possible that the Vasotop will stop working?                                                                                                    

A. The Vasotop may stop having such a beneficial effect on your pet if the heart disease is getting progressively worse. If you see signs of deterioration in your pet then contact your vet as soon as possible.

 

Q. How often should my dog be rechecked at the vets?                                                                                            

A. This will need to be done regularly to start with then can be less often if your pet is stable. Rechecks are usually no less then every 6 months but the exact schedule will be determined by your vet.


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