Disease and Illnesses of dogs – Heart Failure - Cardisure

What is Cardisure?

Cardisure is a tablet that contains the active ingredient Pimobendan which is used in the control of heart disease in dogs. Cardisure is manufactured by Eurovet Animal Health Limited. Cardisure comes as round, brown tablets in several different sizes so that different sized animals can be dosed accurately. The tablets can be scored and divided. Cardisure is a POM-V (Prescription Only Medication) which means it can only be obtained from the vet who is looking after your pet or with a prescription from them.

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 What is Cardisure used for?

Cardisure is used in the treatment of heart failure in dogs. Heart failure can occur for a number of reasons and the medication required depends on the underlying cause. The active ingredient in Cardisure, pimobendan, is used in cases of dilated cardiomyopathy where the heart is enlarged or in cases of valvular insufficiency, where the valves in the heart leak and blood flow can be disrupted. Cardisure can be used alone but in many cases will be combined with other heart medications such as frusemide. Use of Cardisure has been shown to improve both quality of life and life expectancy in dogs with heart failure.

 Cardisure Tips

  • Cardisure should only be used as directed by your vet
  • Cardisure contains the active ingredient pimobendan
  • The dose of Cardisure will be based on your pet’s weight so weigh them regularly
  • Cardisure comes in different sized tablets so accurate doses can be given easily
  • Cardisure tablets are scored and can be divided
  • Cardisure should be stored out of reach of dogs and children
  • Cardisure will often be combined with other drugs
  • Cardisure should be given twice daily, by mouth
  • If there is any change in your pet’s condition while taking Cardisure then contact your vet immediately.

 Side Effects of Cardisure

  • Cardisure is generally a very safe drug when used as directed by your vet
  • Cardisure can cause vomiting and diarrhoea, lethargy and Inappetance
  • These side effects are usually mild and temporary
  • The potential side effects of Cardisure are dose dependant
  • The side effects can be improved by reducing the dose of Cardisure
  • Cardisure has not been tested in pregnant or lactating bitches so the risks need to be weighed against the benefits before using in these animals
  • If you suspect any side effects from Cardisure then contact your vet for advice

An overdose of Cardisure can cause vomiting and a fast heart rate. If you suspect an overdose, contact your vet immediately

Cardisure should be used with care in animals that have existing liver disease or diabetes

 Dosage and Administration of Cardisure

  • The dose of Cardisure will depend on your pet’s weight and will be determined by your vet
  • Cardisure comes as 1.25mg, 2.5mg, 5mg and 10mg tablets
  • Cardisure tablets are round, light brown in colour, and scored in quarters
  • Cardisure tablets can be divided to help with accurate dosing
  • Cardisure tablets are flavoured to  make administration easier
  • Cardisure tablets should be given twice daily, by mouth
  • It is best to give Cardisure on an empty stomach as it improves absorption
  • Do not alter the dose of Cardisure without consulting your vet
  • Cardisure tablets will often be combined with other medications

 Further Information about Cardisure

Cardisure contains the active ingredient pimobendan. Cardisure is used to treat cases of congestive heart failure where the underlying cause is a dilated heart, known as dilated cardiomyopathy or where the cause is due to a leaking heart valve, also called valvular insufficiency. Cardisure comes as round, light brown, flavoured tablets in a range of sizes. Cardisure comes as 1.25mg, 2.5mg, 5mg and 10mg tablets which are scored so that they can be divided for ease of accurate dosing and are also flavoured to make administration easier. Cardisure is classed as a POM-V which means that it can only be obtained from your vet or with a prescription from them.

Pimobendan, the active ingredient in Cardisure, works by causing the heart to pump faster and more strongly which increases the oxygen delivery to the rest of the body. It does this by increasing the sensitivity of the heart muscle to calcium.

Cardisure is best absorbed by the body if it is given on an empty stomach, this is called the drug’s bioavailability.  It is therefore best to give Cardisure an hour before food. Cardisure can have some side effects but these are generally mild and often dose dependant so can often be resolved by simply lowering the dose. These include pets going off their food, becoming lethargic, vomiting or having diarrhoea. If you suspect that your pet is having any side effects from Cardisure then contact your vet for advice.

Further Information about Dosage and Administration of Cardisure

Cardisure is given orally in tablet form. As mentioned above, the tablets come in several sizes so that accurate doses can be given. The tablets are flavoured and scored so that they can be divided into quarters if needed. The dose of Cardisure that your pet needs will depend on their weight so weigh them regularly. Cardisure should be administered on an empty stomach, around an hour before food as it is absorbed much better by the body in that situation.

There is a dose range for Cardisure so that the dose can be altered depending on the severity of the disease. The range is 0.2-0.6mg of the active ingredient, pimobendan, per kilogram of bodyweight per day. This total dose should be divided into two equal doses and given 12 hours apart. Your vet is likely to start your pet at the lower end of the dose rate and then if there is no response to treatment or if the heart disease worsens then there is scope to increase the dose of Cardisure.

Care should be taken in administering Cardisure to patients with pre existing liver disease as pimobendan is metabolised in the liver. Animals who have diabetes should also be closely monitored when being given Cardisure as it can cause insulin release which will interfere with the treatment of diabetes. The safety of Cardisure has not been assessed in pregnant or lactating bitches so in cases where these animals may require treatment for heart disease, a thorough analysis of the risks and benefits should be done.

Frequently Asked Questions about Cardisure

Q. What is Cardisure?                                                                                                                             

A. Cardisure is a drug which contains the active ingredient pimobendan and it is used to control heart failure in dogs.

Q. How is Cardisure given?                                                                                                                                 

A. Cardisure is given as a tablet. The exact dose will be determined by your vet.

Q. Can Cardisure tablets be broken into food?                                                                                                           

A. Cardisure tablets can be divided but they should be given on an empty stomach as they are better absorbed by the body that way.

Q. How long will my pet need to take Cardisure for?                                                                                        

A. Once started, treatment for heart failure is usually lifelong.

Q. How often will I need to recheck with the vet once my pet is taking Cardisure?                  

A. Rechecks will be frequent to start with but if your pet is responding well to treatment then they may be extended to once every 6 months

Q. What should I do if I miss a dose of Cardisure?

A. Just give the next dose as normal, you do not need to give an increased dose the next time

Q. My pet has got hold of the Cardisure and eaten several tablets, what should I do?            

A. If you suspect an overdose, call your vet for advice immediately and monitor your pet for vomiting.

Q. My dog seems to be deteriorating, should I give more Cardisure?                                                             

A. No, you should contact your vet for advice, do not alter the dose without consulting with the vet.

Q. How will I know if the heart disease is getting worse?                                                                                   

A. You will see signs such as lethargy, exercise intolerance and coughing and you should at that point recheck with your vet.


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