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Megestrol acetate is a potent progestagen with marked anti-oestrogenic properties. It is recommended for administration by the oral route in bitches for the postponement or prevention of oestrus and the treatment of hypersexuality which may be manifest as undesirable behaviour in male dogs.In cats it is recommended for prevention or postponement of oestrus and the treatment of miliary dermatitis and eosinophilic granulomata.